Loading stockRelated stocks: Pharmaceutical Preparations
Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.
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Loading stockRelated stocks: Pharmaceutical Preparations
Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.
We are a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. We are developing verekitug, the only known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin ( TSLP ), a cytokine which is a clinically validated driver of inflammatory response positioned ups…
$7.02
+$0.01 (+0.14%)
Live · 05:20 PM
The business is unprofitable at the operating level (-5618.82% margin). The thesis depends entirely on whether and when it reaches sustainable profitability.
Revenue grew 20.4%, still solid. Margins contracted 2337.6pp, which offsets some of the top-line progress.
ROIC dropped from -26.03% to -31.16%, capital efficiency is deteriorating. Negative free cash flow of -$133M. The business is consuming cash, not generating it.
Based on TTM earnings · Diluted shares
Profitability & Returns
Revenue (TTM)
$3M
▲ +20.4% YoY
Net Income (TTM)
-$157M
▼ -128.4% YoY
Op. Margin
-5176.49%
▼ -2337.6pp YoY
ROIC
-37.82%
▼ -5.1pp YoY
Cash Flow & Balance Sheet
FCF (TTM)
-$140M
▼ -123.6% YoY
Op. Cash Flow (TTM)
-$140M
▼ -125.2% YoY
Net Debt
-$293M
Net Cash Position
Cash & Equiv.
$295M
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Upstream Bio (UPB)'s valuation is best read against its own history, its peers, and the growth its price implies. A high multiple is not the same as overvalued: fast-growing, high-quality businesses can deserve a premium. See the general approach in how to tell if a stock is overvalued.
On quality, Upstream Bio scores 25/100 on Intrinsiqq's quality scorecard (a lower-quality business on these measures), weighing growth, margins, returns on capital, share count, and balance-sheet strength. All figures are computed from SEC filings; read the full . This is analysis, not investment advice.
Upstream Bio scores 25 out of 100 on Intrinsiqq's quality score, a weighted blend of 6 metrics each scored 0 to 100, which makes it a lower-quality business on these measures. Recent fundamentals include a -5,176.5% operating margin and a -37.8% return on invested capital. The score weighs revenue and free-cash-flow growth, operating margins, return on invested capital, share-count change, and balance-sheet strength, all computed from SEC filings, not opinion. Because valuation only means something relative to quality, the full metric-by-metric breakdown is on the quality scorecard.
That depends on valuation and quality together, not either alone. you should weigh UPB's valuation and scores 25/100 on quality (lower-quality). A cheap price is only a bargain if the business is durable, and a premium can be justified by genuine quality, so the two questions, "is it cheap?" and "is it good?", only make sense side by side. Read the valuation against the quality scorecard, run the DCF on your own assumptions, and decide for yourself. This is analysis from SEC filings, not investment advice.