Intrinsiqq
SB

ALPS Medical Breakthroughs ETF

SBIOETF · NYSE Arca

$56.25

+$0.16 (+0.29%)

EOD Oct 29, 2026

Compare SBIO with another ETF

Key facts

Expense ratio
0.5%
Dividend yield (TTM)
0.00%
Distributions
Annual
Fund net assets (May 2026)
$162M
Stocks held
82
Other positions
3
Turnover (last fiscal year)
58%
52-week range
$43.10 to $70.85

Top 10 holdings

All holdings

34.8% of assets in ten stocks, as of May 31, 2026

SBIO top 10 holdings by weight
CompanyWeightQuality
Alkermes plcALKS4.48%40
Kymera Therapeutics Inc.KYMR4.23%25
Celcuity Inc.CELC3.92%n/a
Mirum Pharmaceuticals Inc.MIRM3.90%30
Spyre Therapeutics, Inc.SYRE3.68%10
CG Oncology, Inc.CGON3.35%40
Apogee Therapeutics Inc.APGE2.93%n/a
Xenon Pharmaceuticals Inc.XENE2.90%10
Travere Therapeutics Inc.TVTX2.77%45
Dianthus Therapeutics Inc.DNTH2.64%10

Sector allocation

Share of the fund's assets

  • Healthcare99.5%

Scores of what it owns

Every holding's score

Each holding's score, weighted by its size in the fund

28Qualityout of 1000Dividendout of 100

3% of the fund's stock weight sits in companies with a Quality score above 75, 68% in companies below 50.

Where it invests

Stock weight by the company's home country

  • United States80.2%
  • Netherlands4.7%
  • Cayman Islands4.7%
  • Ireland4.5%
  • Canada2.9%
  • Belgium1.2%
  • United Kingdom1.1%
  • Switzerland0.8%

Growth of $10,000

With and without the dividends reinvested

SBIO has not paid a dividend in the last twelve months; the last payment was ex-dividend Dec 19, 2024.

Average annual returns

Total return at net asset value, to May 31, 2026, as reported to the SEC

SBIO average annual total returns
1 year5 years10 years
87.52%3.85%8.81%

Past returns say nothing certain about future ones.

SBIO questions

What does SBIO invest in?+

ALPS Medical Breakthroughs ETF is an exchange-traded fund. Its largest holdings are Alkermes plc (4.48%), Kymera Therapeutics Inc. (4.23%), Celcuity Inc. (3.92%).

What is SBIO's expense ratio?+

0.5% a year, as stated in the fund's latest shareholder report filed with the SEC. On a $10,000 investment that is about $50.00 a year.

How good are the companies SBIO owns?+

Weighted by position size, the stocks in SBIO average a Quality score of 28 out of 100. 3% of the fund's stock weight sits in companies scoring above 75, 68% in companies below 50. The score is computed from each company's SEC filings; the methodology page lists every check.

More on SBIO: Holdings · Dividend history

Holdings: the fund's latest SEC Form N-PORT, as of May 31, 2026. Expense ratio, turnover and returns: the fund's shareholder report (SEC Form N-CSR) for the period to May 31, 2026. Net assets: SEC Form N-PORT. Quality scores: computed by Intrinsiqq from each company's SEC filings (methodology). Price: end of day Oct 29, 2026.

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Not financial advice. Analytical data for research only.

Intrinsiqq is a Netherlands-based company operating in Rotterdam, KvK 73238007.