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Silence Therapeutics plc

SLN

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Valuation & Multiples

Based on TTM earnings · Diluted shares

Market Cap$2.80B
EPS-$0.44
P/E-44.89
P/FCF-66.23
EV/EBITDA-39.93
FCF Yield–
Div. Yield–
Net Debt/FCF1.7x
Silence Therapeutics plc intrinsic value
52-Week Range
$4.30$19.80

Profitability & Returns

Revenue (TTM)

$615K

▼ -98.7% YoY

Net Income (TTM)

-$60M

▼ -95.6% YoY

Op. Margin

-11106.83%

▼ -16146.5pp YoY

ROIC

-96.01%

▼ -9.3pp YoY

Cash Flow & Balance Sheet

FCF (TTM)

-$42M

▲ +8.1% YoY

Op. Cash Flow (TTM)

-$42M

▲ +7.9% YoY

Net Debt

-$72M

Net Cash Position

Cash & Equiv.

$72M

3Y CAGR: -70.4%

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Peers

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Held by ETFs

SLN is in 5 US ETFs. The largest of them, with SLN's weight in each:

Silence Therapeutics (SLN) in four numbers

Fair value (revenue)
$0.01
Price $19.75 is 236376% above it.
Intrinsic Value
Quality score
10/100
Best check: net debt, -$72M. Weakest: return on capital, -96.0%.
Quality
Dividend
None
No dividend in the SEC filings we hold.
Dividends
P/E
-44.89
Negative: a loss over the last twelve months. Price to free cash flow -66.23.
Financials

Questions about Silence Therapeutics

Is Silence Therapeutics (SLN) overvalued?

At $19.75, Silence Therapeutics' price is 236376% above the $0.01 a share fair value that Intrinsiqq's calculator gets from its revenue. The growth behind that figure is yours to set on the Intrinsic Value tab. See how to tell if a stock is overvalued.

What is Silence Therapeutics' fair value?

Intrinsiqq's calculator puts Silence Therapeutics' fair value at $0.01 a share. It grows revenue per share 0% a year for 5 years, applies an exit P/S of 3.1, and works back at a 10% yearly return. A 25% margin of safety gives a buy-below price of $0.01. Every input can be changed on the Intrinsic Value tab.

Is Silence Therapeutics a high-quality business?

Silence Therapeutics scores 10 out of 100 on Intrinsiqq's quality score, which makes it a lower-quality business on these measures. The score blends 6 checks computed from SEC filings. Its best check is net debt at -$72M, and its weakest is return on capital at -96.0%. The Quality tab shows every check against its target.

Does Silence Therapeutics (SLN) pay a dividend?

No. Silence Therapeutics (SLN) does not pay a dividend, and no dividend payment appears anywhere in the filing history we hold. Nor has its share count fallen meaningfully over the last twelve months, so cash is kept in the business. The Dividends tab shows its cash returns.

Source: 10-Q filed 31 Jul 2026 (period ending 30 Jun 2026), SEC. Price: last close 30 Oct 2026. How this is calculated. Sector medians are approximate S&P 500 benchmarks and update periodically. Analysis, not investment advice.

Spot a number that looks wrong? Check it in SLN's SEC filings or

Download this analysis as a PDF (Pro)

Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.

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Not financial advice. Analytical data for research only.

Intrinsiqq is a Netherlands-based company operating in Rotterdam, KvK 73238007.