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Protagonist Therapeutics Inc. Quality Score

PTGX

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Quality54

Valuation is the primary weakness (avg 40/100). No single area scores well.

Broad-market heuristics · Not a buy/sell signal

Valuation and growth

Earnings Multiple
40/100
139.2x

Above 30x, priced for sustained outperformance

Cash Flow Multiple
40/100
71.0x

Above 30x, cash flow yield is thin

Revenue Growth
100/100
80.5%

Above 10% CAGR, strong compounder

Cash Flow Growth
0/100
-15.5%

Below 2%, essentially flat

Business Quality & Capital Allocation

Share Dilution
0/100
44.8%

Heavy dilution above 5%

Margin Trend
100/100
+514.9pp

Expanded 3+pp, strong improvement

Capital Structure
100/100
-$773M

Net cash position, no leverage concern

2022
$237M
$4.00M
2023
$342M
$1.00M
2024
$419M
$11.0M
2025
$567M
$10.0M
TTM
$783M
$9.00M
CashDebt
Return on Capital
40/100
8.1%

8–10%, clearing the bar

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Protagonist Therapeutics (PTGX) quality: score, margins and returns

Protagonist Therapeutics (PTGX) scores 54/100 on Intrinsiqq's quality score (a mixed business), a weighted blend of 8 metrics each scored 0 to 100, on 20.7% operating margins and 8.1% ROIC. Every metric is computed from SEC filings; this is analysis, not investment advice.

Frequently asked

Is Protagonist Therapeutics (PTGX) a high-quality business?+

Protagonist Therapeutics scores 54 out of 100 on Intrinsiqq's quality score, a weighted blend of 8 metrics each scored 0 to 100, which rates it a mixed business on these measures. Recent figures include a 20.7% operating margin and a 8.1% return on invested capital. Quality and price are separate questions: even a great business can be a poor investment if you overpay, so read this score alongside the valuation. The metric-by-metric breakdown is on this scorecard.

What does Protagonist Therapeutics's quality score measure?+

Intrinsiqq's quality score weighs revenue and free-cash-flow growth, operating margins, return on invested capital, change in share count, and balance-sheet strength, each computed from PTGX's SEC filings rather than opinion or sentiment. A higher score means a more durable, capital-efficient business; it is not a buy or sell signal. Open each metric on this page to see exactly where Protagonist Therapeutics scores well and where it falls behind.

What is Protagonist Therapeutics's return on invested capital (ROIC)?+

Protagonist Therapeutics earns about 8.1% on its invested capital, which is modest. ROIC measures how much profit a company generates per dollar put to work; sustained ROIC above its cost of capital is one of the clearest signs of a real competitive moat. Compare it to PTGX's margins and growth on this scorecard to judge durability.

How profitable is Protagonist Therapeutics?+

Protagonist Therapeutics runs an operating margin of about 20.7% and a net margin of about 29.4%. Revenue has grown at roughly 10.0% a year recently. High, stable margins usually point to pricing power and operating discipline. Margins are most telling next to growth and returns on capital, all of which feed this quality score. This is analysis from SEC filings, not investment advice.

How the market compares: US profitability statistics

SourceQuality score computed from the 10-Q filed 31 Jul 2026, covering the period ending 30 Jun 2026, as reported to the SEC. Data last refreshed 14 Oct 2026. How this is calculated.

Fiscal year ends Dec. Sector medians are approximate S&P 500 benchmarks and update periodically. Checks use broad-market heuristics, so sector norms may differ, and the valuation checks are more cyclical than the quality checks.

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Held by ETFs

PTGX is in 109 US ETFs. The largest of them, with PTGX's weight in each:

Spot a number that looks wrong? Check it in PTGX's SEC filings or

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Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.

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