Denali Therapeutics Inc. Insider Trading

DNLI

Last 12 months

Insiders sold $1.3M and bought nothing on the open market.

25% of the selling was scheduled in advance under 10b5-1 plans. No executive or director has bought shares on the open market in the last two years.

Net open-market

−$1.3M

0 buys · 6 sales

Under a 10b5-1 plan

25%

of the value sold

Insiders who bought / sold

0 / 4

executives and directors

Last open-market buy

None

in the last two years

Get an email when DNLI's executives or directors buy, or make a large sale outside a plan.

Trades · last 2 years

Date	Insider	Trade	Shares	Price	Value	Of their stake	Filing
Sep 4	Peter Scott Chin Chief Medical Officer	SoldNo plan	1,654	$22.29	37K	0.8%	Form 4
Sep 2	Nancy Thornberry Director	Sold10b5-1 plan 2 parts	11,439	$22.90 average	262K	37%	Form 4
Sep 1	Alexander O. Schuth COFO and Secretary	Sold10b5-1 plan	2,768	$23.44	65K	0.3%	Form 4
Aug 11	Alexander O. Schuth COFO and Secretary	SoldNo plan	2,857	$25.07	72K	0.4%	Form 4
Jan 6	Alexander O. Schuth COFO and Secretary	SoldNo plan	17,218	$16.50	284K	2.1%	Form 4
Jan 6	Ryan J. Watts President and CEO	SoldNo plan	35,198	$16.50	581K	1.4%	Form 4
Aug 12, 2025 – Aug 13, 2025	Carole Ho Chief Medical Officer	Sold10b5-1 plan 2 parts	3,743	$13.81 average	52K	0.9%	Form 4
Aug 12, 2025	Alexander O. Schuth COFO and Secretary	SoldNo plan	2,937	$13.58	40K	0.4%	Form 4
Jul 9, 2025	Ryan J. Watts President and CEO	Sold10b5-1 plan	495,282	$15.00	$7.43M	17%	Form 4
Jan 6, 2025 – Jan 7, 2025	Carole Ho Chief Medical Officer	SoldNo plan 2 parts	15,162	$20.33 average	308K	4.1%	Form 4
Jan 6, 2025 – Jan 7, 2025	Alexander O. Schuth COFO and Secretary	SoldNo plan 2 parts	15,162	$20.33 average	308K	1.9%	Form 4
Jan 6, 2025 – Jan 7, 2025	Ryan J. Watts President and CEO	SoldNo plan 2 parts	36,916	$20.34 average	751K	1.5%	Form 4
Jan 7, 2025	Steve E. Krognes Director	SoldNo plan	3,339	$20.81	69K	0.4%	Form 4
Jan 2, 2025	Vicki L Sato Director	Sold10b5-1 plan	3,080	$20.91	64K	2.8%	Form 4
Dec 31, 2024	Steve E. Krognes Director	Sold10b5-1 plan	30,000	$20.25	608K	3.6%	Form 4
Nov 11, 2024	David P Schenkein Director	Sold10b5-1 plan 2 parts	59,441	$32.51 average	$1.93M	63%	Form 4
Nov 7, 2024	Alexander O. Schuth COFO and Secretary	Sold10b5-1 plan 3 parts	15,558	$29.91 average	465K	2.2%	Form 4
Nov 7, 2024	Vicki L Sato Director	Sold10b5-1 plan	1,020	$30.00	31K	0.9%	Form 4

Sep 4No plan
Peter Scott Chin
Chief Medical Officer · sold 1,654 at $22.29
37K
0.8% of stake
Sep 210b5-1 plan
Nancy Thornberry
Director · sold 11,439 at avg $22.90
262K
37% of stake
Sep 110b5-1 plan
Alexander O. Schuth
COFO and Secretary · sold 2,768 at $23.44
65K
0.3% of stake
Aug 11No plan
Alexander O. Schuth
COFO and Secretary · sold 2,857 at $25.07
72K
0.4% of stake
Jan 6No plan
Alexander O. Schuth
COFO and Secretary · sold 17,218 at $16.50
284K
2.1% of stake
Jan 6No plan
Ryan J. Watts
President and CEO · sold 35,198 at $16.50
581K
1.4% of stake
Aug 12, 2025 – Aug 13, 202510b5-1 plan
Carole Ho
Chief Medical Officer · sold 3,743 at avg $13.81
52K
0.9% of stake
Aug 12, 2025No plan
Alexander O. Schuth
COFO and Secretary · sold 2,937 at $13.58
40K
0.4% of stake
Jul 9, 202510b5-1 plan
Ryan J. Watts
President and CEO · sold 495,282 at $15.00
$7.43M
17% of stake
Jan 6, 2025 – Jan 7, 2025No plan
Carole Ho
Chief Medical Officer · sold 15,162 at avg $20.33
308K
4.1% of stake
Jan 6, 2025 – Jan 7, 2025No plan
Alexander O. Schuth
COFO and Secretary · sold 15,162 at avg $20.33
308K
1.9% of stake
Jan 6, 2025 – Jan 7, 2025No plan
Ryan J. Watts
President and CEO · sold 36,916 at avg $20.34
751K
1.5% of stake
Jan 7, 2025No plan
Steve E. Krognes
Director · sold 3,339 at $20.81
69K
0.4% of stake
Jan 2, 202510b5-1 plan
Vicki L Sato
Director · sold 3,080 at $20.91
64K
2.8% of stake
Dec 31, 202410b5-1 plan
Steve E. Krognes
Director · sold 30,000 at $20.25
608K
3.6% of stake
Nov 11, 202410b5-1 plan
David P Schenkein
Director · sold 59,441 at avg $32.51
$1.93M
63% of stake
Nov 7, 202410b5-1 plan
Alexander O. Schuth
COFO and Secretary · sold 15,558 at avg $29.91
465K
2.2% of stake
Nov 7, 202410b5-1 plan
Vicki L Sato
Director · sold 1,020 at $30.00
31K
0.9% of stake

How to read this. Insiders sell for many reasons: taxes, diversifying, a house. Open-market buys are rarer and say more. A 10b5-1 plan is a trading schedule set up months in advance, so those sales were not timed on news. Large holders (funds and 10% owners) are listed under Everything but not counted as insiders. If you own or watch DNLI, we send a push when an executive buys or makes a large sale outside a plan.

Source: SEC Form 4 filings, filed within two business days of each trade and checked for new ones every hour.

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Held by ETFs

DNLI is in 56 US ETFs. The largest of them, with DNLI's weight in each:

Spot a number that looks wrong? Check it in DNLI's SEC filings or

Download this analysis as a PDF (Pro)

Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.

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