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Vertex Pharmaceuticals Incorporated Quality Score

VRTX

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Quality47

Growth is the primary weakness (avg 35/100). Business quality is the relative bright spot.

Broad-market heuristics · Not a buy/sell signal

Valuation and growth

Earnings Multiple
40/100
32.0x

Above 30x, priced for sustained outperformance

Cash Flow Multiple
40/100
36.7x

Above 30x, cash flow yield is thin

Revenue Growth
70/100
9.0%

5–10% CAGR, steady but not exceptional

Cash Flow Growth
0/100
-0.8%

Below 2%, essentially flat

Business Quality & Capital Allocation

Share Dilution
80/100
-1.5%

Roughly flat, no meaningful dilution

Margin Trend
0/100
-10.3pp

Contracted >2pp, margin pressure

Capital Structure
100/100
-$5.87B

Net cash position, no leverage concern

2022
$10.8B
$900M
2023
$11.2B
$808M
2024
$6.12B
$1.75B
2025
$6.61B
$2.04B
TTM
$7.85B
$1.98B
CashDebt
Return on Capital
80/100
18.7%

15–20%, well above cost of capital

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Vertex Pharmaceuticals (VRTX) quality: score, margins and returns

Vertex Pharmaceuticals (VRTX) scores 47/100 on Intrinsiqq's quality score (a mixed business), a weighted blend of 8 metrics each scored 0 to 100, on 38.0% operating margins and 18.7% ROIC. Every metric is computed from SEC filings; this is analysis, not investment advice.

Frequently asked

Is Vertex Pharmaceuticals (VRTX) a high-quality business?+

Vertex Pharmaceuticals scores 47 out of 100 on Intrinsiqq's quality score, a weighted blend of 8 metrics each scored 0 to 100, which rates it a mixed business on these measures. Recent figures include a 38.0% operating margin and a 18.7% return on invested capital. Quality and price are separate questions: even a great business can be a poor investment if you overpay, so read this score alongside the valuation. The metric-by-metric breakdown is on this scorecard.

What does Vertex Pharmaceuticals's quality score measure?+

Intrinsiqq's quality score weighs revenue and free-cash-flow growth, operating margins, return on invested capital, change in share count, and balance-sheet strength, each computed from VRTX's SEC filings rather than opinion or sentiment. A higher score means a more durable, capital-efficient business; it is not a buy or sell signal. Open each metric on this page to see exactly where Vertex Pharmaceuticals scores well and where it falls behind.

What is Vertex Pharmaceuticals's return on invested capital (ROIC)?+

Vertex Pharmaceuticals earns about 18.7% on its invested capital, which is strong. ROIC measures how much profit a company generates per dollar put to work; sustained ROIC above its cost of capital is one of the clearest signs of a real competitive moat. Compare it to VRTX's margins and growth on this scorecard to judge durability.

How profitable is Vertex Pharmaceuticals?+

Vertex Pharmaceuticals runs an operating margin of about 38.0% and a net margin of about 35.0%. Revenue has grown at roughly 14.1% a year recently. High, stable margins usually point to pricing power and operating discipline. Margins are most telling next to growth and returns on capital, all of which feed this quality score. This is analysis from SEC filings, not investment advice.

How the market compares: US profitability statistics

SourceQuality score computed from the 10-Q filed 31 Jul 2026, covering the period ending 30 Jun 2026, as reported to the SEC. Data last refreshed 14 Oct 2026. How this is calculated.

Fiscal year ends Dec. Sector medians are approximate S&P 500 benchmarks and update periodically. Checks use broad-market heuristics, so sector norms may differ, and the valuation checks are more cyclical than the quality checks.

Peers

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Held by ETFs

VRTX is in 379 US ETFs. The largest of them, with VRTX's weight in each:

Spot a number that looks wrong? Check it in VRTX's SEC filings or

Download this analysis as a PDF (Pro)

Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.

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