Valuation is the primary weakness (avg 0/100). No single area scores well.
Broad-market heuristics · Not a buy/sell signal
Valuation and growth
Valuation
Growth
Negative earnings, no valuation support
Negative FCF, no valuation support
Above 10% CAGR, strong compounder
FCF negative, burning cash after capex
Business Quality & Capital Allocation
Heavy dilution above 5%
Expanded 3+pp, strong improvement
Net cash position, no leverage concern
Below 8%, may not cover cost of capital
Taysha Gene Therapies (TSHA) quality: score, margins and returns
Taysha Gene Therapies (TSHA) scores 40/100 on Intrinsiqq's quality score (a mixed business), a weighted blend of 6 metrics each scored 0 to 100, on -2,792.3% operating margins and -36.4% ROIC. Every metric is computed from SEC filings; this is analysis, not investment advice.
Frequently asked
Is Taysha Gene Therapies (TSHA) a high-quality business?+
Taysha Gene Therapies scores 40 out of 100 on Intrinsiqq's quality score, a weighted blend of 6 metrics each scored 0 to 100, which rates it a mixed business on these measures. Recent figures include a -2,792.3% operating margin and a -36.4% return on invested capital. Quality and price are separate questions: even a great business can be a poor investment if you overpay, so read this score alongside the valuation. The metric-by-metric breakdown is on this scorecard.
What does Taysha Gene Therapies's quality score measure?+
Intrinsiqq's quality score weighs revenue and free-cash-flow growth, operating margins, return on invested capital, change in share count, and balance-sheet strength, each computed from TSHA's SEC filings rather than opinion or sentiment. A higher score means a more durable, capital-efficient business; it is not a buy or sell signal. Open each metric on this page to see exactly where Taysha Gene Therapies scores well and where it falls behind.
What is Taysha Gene Therapies's return on invested capital (ROIC)?+
Taysha Gene Therapies earns about -36.4% on its invested capital, which is weak. ROIC measures how much profit a company generates per dollar put to work; sustained ROIC above its cost of capital is one of the clearest signs of a real competitive moat. Compare it to TSHA's margins and growth on this scorecard to judge durability.
How profitable is Taysha Gene Therapies?+
Taysha Gene Therapies runs an operating margin of about -2,792.3% and a net margin of about -2,728.0%. Revenue has grown at roughly 57.5% a year recently. High, stable margins usually point to pricing power and operating discipline. Margins are most telling next to growth and returns on capital, all of which feed this quality score. This is analysis from SEC filings, not investment advice.
SourceQuality score computed from the 10-Q filed 11 Aug 2026, covering the period ending 30 Jun 2026, as reported to the SEC. Data last refreshed 12 Aug 2026. How this is calculated.
Fiscal year ends Dec. Sector medians are approximate S&P 500 benchmarks and update periodically. Checks use broad-market heuristics, so sector norms may differ, and the valuation checks are more cyclical than the quality checks.
Peers
Biological Products, (No Diagnostic Substances) · Pick stocks to compare with TSHA
Held by ETFs
TSHA is in 35 US ETFs. The largest of them, with TSHA's weight in each:
Spot a number that looks wrong? Check it in TSHA's SEC filings or
Download this analysis as a PDF (Pro)
Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.
Keep analysing TSHA
Create a free account and get 14 days of Premium: every stock and every tool.
- Unlimited stocks
- Stock screener
- Portfolio tracker
- Editable DCF
- Compare side by side
- Unlimited alerts
No card. Moves to Free after, unless you upgrade.
Already have an account?
Or come back tomorrow. Stocks on your watchlist are always free to view.