All currency values in $ millions unless otherwise noted
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| Income Statement | DEC 2025 | DEC 2024 ~1.3:1 split | DEC 2023 ~2.7:1 split | DEC 2022 ~2.6:1 split | DEC 2021 5:1 split |
|---|---|---|---|---|---|
| Revenues | |||||
| Revenue | $5 | $3 | $0 | $0 | $0 |
| General & Administrative | $52 | $50 | $43 | $30 | $14 |
| Research & Development | $161 | $155 | $148 | $87 | $71 |
| Total Operating Expenses | $213 | $205 | $205 | $117 | $84 |
| Operating Income | -$208 | -$202 | -$205 | -$117 | -$84 |
| Non-Operating | |||||
| Net Interest Expense | $4 | $4 | $3 | – | – |
| Other Non-Operating Income (Expense) | $7 | $7 | $6 | -$6 | -$81 |
| Income Tax Expense | $0 | $0 | -$0 | -$1 | -$0 |
| Net Income | |||||
| Net Income | -$201 | -$196 | -$198 | -$122 | -$165 |
| Per Share Data | |||||
| Revenue Per Share | $0.03 | $0.03 | $0.00 | $0.00 | $0.00 |
| EPS (Basic) | -$1.35 | -$1.65 | -$2.18 | -$4.19 | -$14.19 |
| EPS (Diluted) | -$1.35 | -$1.65 | -$2.18 | -$4.19 | -$14.19 |
| Weighted Avg Shares (Basic) | 148.8M | 118.6M | 91.0M | 33.9M | 13.0M |
| Weighted Avg Shares (Diluted) | 148.8M | 118.6M | 91.0M | 33.9M | 13.0M |
| Shares Outstanding | 148.8M | 118.6M | 91.0M | 33.9M | 13.0M |
Prime Medicine (PRME) financials: revenue, profit and margins
Prime Medicine (PRME) generated about n/a in revenue and -$188 million in net income (a -4,342.4% net margin) over the trailing twelve months, growing at roughly -5.7% a year. Figures are from SEC filings; this is analysis, not investment advice.
Frequently asked
Is Prime Medicine profitable?+
Prime Medicine reported about -$188 million in net loss over the trailing twelve months, a net margin of roughly -4,342.4%. Net income is the bottom line after all costs, interest and taxes. Compare it to free cash flow on this tab, since reported profit and actual cash generated can diverge.
What are Prime Medicine's profit margins?+
Prime Medicine runs an operating margin of about -4,498.1%, a net margin of about -4,342.4%. Margins show how much of each sales dollar a company keeps at each stage. Stable or rising margins usually signal pricing power and cost discipline; falling margins are worth investigating. See the multi-year trend on this tab.
How fast is Prime Medicine growing?+
Prime Medicine's revenue has compounded at roughly -5.7% a year over the past five years. Growth only creates value when it is profitable and cash-generative, so read this rate alongside PRME's margins and free cash flow. This is analysis from SEC filings, not investment advice.
SourceFinancial statements computed from the 10-Q filed 31 Jul 2026, covering the period ending 30 Jun 2026, as reported to the SEC. Data last refreshed 17 Sept 2026. How this is calculated.
Fiscal year ends Dec.
Peers
Biological Products, (No Diagnostic Substances) · Pick stocks to compare with PRME
Held by ETFs
PRME is in 22 US ETFs. The largest of them, with PRME's weight in each:
Vanguard Health Care ETFVHT0.00%of the fund
iShares Russell 2000 Growth ETFIWO0.03%of the fund
State Street SPDR S&P Biotech ETFXBI0.19%of the fund
iShares Biotechnology ETFIBB0.03%of the fund
Fidelity MSCI Health Care Index ETFFHLC0.00%of the fund
State Street SPDR Portfolio MSCI Global Stock Market ETFSPGM0.01%of the fund
Spot a number that looks wrong? Check it in PRME's SEC filings or
Download this analysis as a PDF (Pro)
Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.
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