Praxis Precision Medicines Inc. Insider Trading

PRAX

Last 12 months

Insiders sold $11.1M and bought nothing on the open market.

33% of the selling was scheduled in advance under 10b5-1 plans. General Counsel and Secretary Alex Nemiroff sold $4.85M on Nov 20, 2025, 55% of their stake, outside a plan. The last open-market buy by an executive or director was in Oct 2023.

Net open-market

−$11.1M

0 buys · 3 sales

Under a 10b5-1 plan

33%

of the value sold

Insiders who bought / sold

0 / 3

executives and directors

Last open-market buy

Oct 2023

Oct 5, 2023

Get an email when PRAX's executives or directors buy, or make a large sale outside a plan.

Trades · last 2 years

Date	Insider	Trade	Shares	Price	Value	Of their stake	Filing
Jun 24	Jill Desimone Director	Sold10b5-1 plan 12 parts	11,600	$311.32 average	$3.61M	83%	Form 4
Nov 20, 2025	Alex Nemiroff General Counsel and Secretary	SoldNo plan 4 parts	25,130	$193.08 average	$4.85M	55%	Form 4
Nov 20, 2025	Lauren Mastrocola Principal Accounting Officer	SoldNo plan 2 parts	13,600	$192.08 average	$2.61M	57%	Form 4
Oct 16, 2025	Phillip Gross Large holder	SoldNo plan 10 parts	313,910	$105.76 average	$33.2M	7.6%	Form 4
Nov 14, 2024	Alex Nemiroff General Counsel and Secretary	SoldNo plan	8,239	$80.20	661K	44%	Form 4
Nov 14, 2024	Lauren Mastrocola Principal Accounting Officer	SoldNo plan	5,188	$81.78	424K	48%	Form 4

Jun 2410b5-1 plan
Jill Desimone
Director · sold 11,600 at avg $311.32
$3.61M
83% of stake
Nov 20, 2025No plan
Alex Nemiroff
General Counsel and Secretary · sold 25,130 at avg $193.08
$4.85M
55% of stake
Nov 20, 2025No plan
Lauren Mastrocola
Principal Accounting Officer · sold 13,600 at avg $192.08
$2.61M
57% of stake
Oct 16, 2025No plan
Phillip Gross
Large holder · sold 313,910 at avg $105.76
$33.2M
7.6% of stake
Nov 14, 2024No plan
Alex Nemiroff
General Counsel and Secretary · sold 8,239 at $80.20
661K
44% of stake
Nov 14, 2024No plan
Lauren Mastrocola
Principal Accounting Officer · sold 5,188 at $81.78
424K
48% of stake

How to read this. Insiders sell for many reasons: taxes, diversifying, a house. Open-market buys are rarer and say more. A 10b5-1 plan is a trading schedule set up months in advance, so those sales were not timed on news. Large holders (funds and 10% owners) are listed under Everything but not counted as insiders. If you own or watch PRAX, we send a push when an executive buys or makes a large sale outside a plan.

Source: SEC Form 4 filings, filed within two business days of each trade and checked for new ones every hour.

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Held by ETFs

PRAX is in 82 US ETFs. The largest of them, with PRAX's weight in each:

Spot a number that looks wrong? Check it in PRAX's SEC filings or

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Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.

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