Valuation is the primary weakness (avg 50/100). Growth is the relative bright spot.
Broad-market heuristics · Not a buy/sell signal
Valuation and growth
Valuation
Growth
Above 30x, priced for sustained outperformance
25–30x, paying up for cash generation
Above 10% CAGR, strong compounder
Business Quality & Capital Allocation
Heavy dilution above 5%
Net cash position, no leverage concern
10–15%, respectable returns
Krystal Biotech (KRYS) quality: score, margins and returns
Krystal Biotech (KRYS) scores 44/100 on Intrinsiqq's quality score (a mixed business), a weighted blend of 6 metrics each scored 0 to 100, on 48.4% operating margins and 14.6% ROIC. Every metric is computed from SEC filings; this is analysis, not investment advice.
Frequently asked
Is Krystal Biotech (KRYS) a high-quality business?+
Krystal Biotech scores 44 out of 100 on Intrinsiqq's quality score, a weighted blend of 6 metrics each scored 0 to 100, which rates it a mixed business on these measures. Recent figures include a 48.4% operating margin and a 14.6% return on invested capital. Quality and price are separate questions: even a great business can be a poor investment if you overpay, so read this score alongside the valuation. The metric-by-metric breakdown is on this scorecard.
What does Krystal Biotech's quality score measure?+
Intrinsiqq's quality score weighs revenue and free-cash-flow growth, operating margins, return on invested capital, change in share count, and balance-sheet strength, each computed from KRYS's SEC filings rather than opinion or sentiment. A higher score means a more durable, capital-efficient business; it is not a buy or sell signal. Open each metric on this page to see exactly where Krystal Biotech scores well and where it falls behind.
What is Krystal Biotech's return on invested capital (ROIC)?+
Krystal Biotech earns about 14.6% on its invested capital, which is solid. ROIC measures how much profit a company generates per dollar put to work; sustained ROIC above its cost of capital is one of the clearest signs of a real competitive moat. Compare it to KRYS's margins and growth on this scorecard to judge durability.
How profitable is Krystal Biotech?+
Krystal Biotech runs an operating margin of about 48.4% and a net margin of about 47.9%. Revenue has grown at roughly 177.0% a year recently. High, stable margins usually point to pricing power and operating discipline. Margins are most telling next to growth and returns on capital, all of which feed this quality score. This is analysis from SEC filings, not investment advice.
SourceQuality score computed from the 10-Q filed 28 Oct 2026, covering the period ending 30 Sept 2026, as reported to the SEC. Data last refreshed 3 Nov 2026. How this is calculated.
Fiscal year ends Dec. Sector medians are approximate S&P 500 benchmarks and update periodically. Checks use broad-market heuristics, so sector norms may differ, and the valuation checks are more cyclical than the quality checks.
Peers
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Held by ETFs
KRYS is in 125 US ETFs. The largest of them, with KRYS's weight in each:
Spot a number that looks wrong? Check it in KRYS's SEC filings or
Download this analysis as a PDF (Pro)
Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.
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