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Structure Therapeutics Inc. American logo

Structure Therapeutics Inc. American

GPCR

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Structure Therapeutics Inc. American Depositary Shares represent ownership interests in Structure Therapeutics, a clinical-stage biopharmaceutical company focused on developing oral small-molecule therapies for chronic metabolic and cardiopulmonary diseases with significant unmet medical needs. The company’s current programs center on medicines designed to target G protein-coupled receptors, a broad and important class of biological pathways involved in disease signaling. Its research pipeline includes candidates aimed at obesity and related metabolic conditions, as well as additional therapeutic areas within chronic disease management. Structure Therapeutics operates as a science-driven drug developer, combining discovery, preclinical work, and clinical-stage development to advance treatments intended for long-term use in specialized medical markets. The American Depositary Shares provide a U.S.-traded equity form for the company’s ordinary shares, giving market participants access to a biopharmaceutical business built around oral therapeutics and targeted receptor biology.

Valuation & Multiples

Based on TTM earnings · Diluted shares

Market Cap$1.59B
EPS-$3.16
P/E-6.91
P/FCF-7.08
EV/EBITDA-0.56
FCF Yield–
Div. Yield–
Net Debt/FCF6.4x
Structure Therapeutics Inc. American intrinsic value
52-Week Range
$21.08$64.94

Profitability & Returns

Revenue (TTM)

$0.00

Net Income (TTM)

-$215M

▼ -15.2% YoY

Op. Margin

–

ROIC

-12.34%

▲ +6.5pp YoY

Cash Flow & Balance Sheet

FCF (TTM)

-$225M

▼ -91.5% YoY

Op. Cash Flow (TTM)

-$220M

▼ -112.7% YoY

Net Debt

-$1.44B

Net Cash Position

Cash & Equiv.

$1.45B

Continue Research

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Held by ETFs

GPCR is in 18 US ETFs. The largest of them, with GPCR's weight in each:

Structure Therapeutics Inc. American (GPCR) in three numbers

Quality score
10/100
Best check: net debt, -$1.44B. Weakest: return on capital, -12.3%.
Quality
Dividend
None
No dividend in the company filings we hold.
Dividends
P/E
-6.91
Negative: a loss over the last twelve months. Price to free cash flow -7.08.
Financials

Questions about Structure Therapeutics Inc. American

Is Structure Therapeutics Inc. American a high-quality business?

Structure Therapeutics Inc. American scores 10 out of 100 on Intrinsiqq's quality score, which makes it a lower-quality business on these measures. The score blends 4 checks computed from company filings. Its best check is net debt at -$1.44B, and its weakest is return on capital at -12.3%. The Quality tab shows every check against its target.

Does Structure Therapeutics Inc. American (GPCR) pay a dividend?

No. Structure Therapeutics Inc. American (GPCR) does not pay a dividend, and no dividend payment appears anywhere in the filing history we hold. Nor has its share count fallen meaningfully over the last twelve months, so cash is kept in the business. The Dividends tab shows its cash returns.

Source: company filings. Price: last close 30 Oct 2026. How this is calculated. Sector medians are approximate S&P 500 benchmarks and update periodically. Analysis, not investment advice.

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Data sourced from company filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.

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