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GH Research PLC

GHRS

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GH Research PLC is a clinical-stage biopharmaceutical company focused on developing treatments for psychiatric and neurological disorders, with an initial emphasis on depression and treatment-resistant depression. Its current pipeline centers on mebufotenin-based therapies, including GH001, an inhalable product candidate being studied for treatment-resistant depression, bipolar II disorder, and postpartum depression, and GH002, an intravenous candidate in early clinical development. The company is centered on research and development and works to advance novel therapeutic options for mental health conditions with significant unmet medical need. Based in Dublin, Ireland, GH Research PLC is positioned in the broader healthcare and biotechnology markets as a specialist developer of psychedelic-inspired medicines.

Valuation & Multiples

Based on TTM earnings · Diluted shares

Market Cap$1.33B
EPS-$1.00
P/E-19.97
P/FCF-25.58
EV/EBITDA-14.64
FCF Yield–
Div. Yield–
Net Debt/FCF5.4x
GH Research PLC intrinsic value
52-Week Range
$12.49$30.64

Profitability & Returns

Revenue (TTM)

$0.00

Net Income (TTM)

-$62M

▼ -23.9% YoY

Op. Margin

–

ROIC

-20.85%

▼ -1.0pp YoY

Cash Flow & Balance Sheet

FCF (TTM)

-$52M

▼ -3.2% YoY

Op. Cash Flow (TTM)

-$52M

▼ -3.0% YoY

Net Debt

-$280M

Net Cash Position

Cash & Equiv.

$281M

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Held by ETFs

GHRS is in 7 US ETFs. The largest of them, with GHRS's weight in each:

GH Research (GHRS) in three numbers

Quality score
10/100
Best check: net debt, -$280M. Weakest: return on capital, -20.9%.
Quality
Dividend
None
No dividend in the company filings we hold.
Dividends
P/E
-19.97
Negative: a loss over the last twelve months. Price to free cash flow -25.58.
Financials

Questions about GH Research

Is GH Research a high-quality business?

GH Research scores 10 out of 100 on Intrinsiqq's quality score, which makes it a lower-quality business on these measures. The score blends 4 checks computed from company filings. Its best check is net debt at -$280M, and its weakest is return on capital at -20.9%. The Quality tab shows every check against its target.

Does GH Research (GHRS) pay a dividend?

No. GH Research (GHRS) does not pay a dividend, and no dividend payment appears anywhere in the filing history we hold. Nor has its share count fallen meaningfully over the last twelve months, so cash is kept in the business. The Dividends tab shows its cash returns.

Source: company filings. Price: last close 4 Nov 2026. How this is calculated. Sector medians are approximate S&P 500 benchmarks and update periodically. Analysis, not investment advice.

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Data sourced from company filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.

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