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Definium Therapeutics Inc.

DFTX

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Definium Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing novel treatments for brain health disorders. The company’s current pipeline centers on psychiatry and neurology, with lead product candidates such as DT120, an orally disintegrating tablet under late-stage study for generalized anxiety disorder and major depressive disorder, and DT402, which is being evaluated for autism spectrum disorder. Definium Therapeutics applies a research-driven approach to psychedelic-derived and other brain-health-focused therapeutics, aiming to address underlying causes of psychiatric and neurological conditions. The company operates from New York and serves the healthcare and biotechnology markets through its drug development programs and clinical research activities.

Valuation & Multiples

Based on TTM earnings · Diluted shares

Market Cap$3.62B
EPS-$3.52
P/E-9.30
P/FCF-21.55
EV/EBITDA-14.28
FCF Yield–
Div. Yield–
Net Debt/FCF2.2x
Definium Therapeutics Inc. intrinsic value
52-Week Range
$10.68$46.18

Profitability & Returns

Revenue (TTM)

$0.00

Net Income (TTM)

-$354M

▼ -69.1% YoY

Op. Margin

–

ROIC

-41.30%

▼ -10.1pp YoY

Cash Flow & Balance Sheet

FCF (TTM)

-$168M

▼ -66.3% YoY

Op. Cash Flow (TTM)

-$168M

▼ -66.3% YoY

Net Debt

-$371M

Net Cash Position

Cash & Equiv.

$412M

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Held by ETFs

DFTX is in 50 US ETFs. The largest of them, with DFTX's weight in each:

Definium Therapeutics (DFTX) in three numbers

Quality score
10/100
Best check: net debt, -$371M. Weakest: return on capital, -41.3%.
Quality
Dividend
None
No dividend in the company filings we hold.
Dividends
P/E
-9.30
Negative: a loss over the last twelve months. Price to free cash flow -21.55.
Financials

Questions about Definium Therapeutics

Is Definium Therapeutics a high-quality business?

Definium Therapeutics scores 10 out of 100 on Intrinsiqq's quality score, which makes it a lower-quality business on these measures. The score blends 4 checks computed from company filings. Its best check is net debt at -$371M, and its weakest is return on capital at -41.3%. The Quality tab shows every check against its target.

Does Definium Therapeutics (DFTX) pay a dividend?

No. Definium Therapeutics (DFTX) does not pay a dividend, and no dividend payment appears anywhere in the filing history we hold. Nor has its share count fallen meaningfully over the last twelve months, so cash is kept in the business. The Dividends tab shows its cash returns.

Source: company filings. Price: last close 4 Nov 2026. How this is calculated. Sector medians are approximate S&P 500 benchmarks and update periodically. Analysis, not investment advice.

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Data sourced from company filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.

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