Apogee Therapeutics Inc. Insider Trading

APGE

Last 12 months

Insiders sold $174M and bought nothing on the open market.

23% of the selling was scheduled in advance under 10b5-1 plans. Director Peter Evan Harwin sold $134M on Jan 22, 81% of their stake, outside a plan. The last open-market buy by an executive or director was in Dec 2024.

Net open-market

−$174M

0 buys · 35 sales

Under a 10b5-1 plan

23%

of the value sold

Insiders who bought / sold

0 / 4

executives and directors

Last open-market buy

Dec 2024

Dec 12, 2024

Get an email when APGE's executives or directors buy, or make a large sale outside a plan.

Trades · last 2 years

Date	Insider	Trade	Shares	Price	Value	Of their stake	Filing
Aug 5	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan	5,500	$134.17	738K	3.2%	Form 4
Jul 8	Michael Thomas Henderson Chief Executive Officer	Sold10b5-1 plan	20,000	$133.63	$2.67M	2.1%	Form 4
Jul 1	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan	5,500	$132.74	730K	3.0%	Form 4
Jun 22	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan	26,400	$132.60	$3.5M	13%	Form 4
Jun 22	Michael Thomas Henderson Chief Executive Officer	Sold10b5-1 plan	80,000	$132.54	$10.6M	7.3%	Form 4
Jun 10	Michael Thomas Henderson Chief Executive Officer	Sold10b5-1 plan 6 parts	20,000	$83.38 average	$1.67M	1.8%	Form 4
Jun 3	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan	5,500	$78.71	433K	2.6%	Form 4
May 13	Michael Thomas Henderson Chief Executive Officer	Sold10b5-1 plan 2 parts	20,000	$82.09 average	$1.64M	1.8%	Form 4
May 6	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan 2 parts	5,500	$84.14 average	463K	2.6%	Form 4
May 1	Jane Henderson Chief Financial Officer	Sold10b5-1 plan 3 parts	2,000	$82.04 average	164K	1.1%	Form 4
Apr 16	Jane Henderson Chief Financial Officer	Sold10b5-1 plan	2,000	$90.00	180K	1.1%	Form 4
Apr 8	Michael Thomas Henderson Chief Executive Officer	Sold10b5-1 plan 3 parts	20,000	$82.58 average	$1.65M	1.7%	Form 4
Apr 1	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan 3 parts	5,500	$84.84 average	467K	2.6%	Form 4
Apr 1	Jane Henderson Chief Financial Officer	Sold10b5-1 plan 2 parts	2,000	$85.01 average	170K	1.1%	Form 4
Mar 25	Jane Henderson Chief Financial Officer	Sold10b5-1 plan	2,000	$85.00	170K	1.1%	Form 4
Mar 11	Michael Thomas Henderson Chief Executive Officer	Sold10b5-1 plan 3 parts	20,000	$74.78 average	$1.5M	1.7%	Form 4
Mar 4	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan 3 parts	5,500	$71.06 average	391K	2.6%	Form 4
Mar 2	Jane Henderson Chief Financial Officer	Sold10b5-1 plan 4 parts	2,000	$70.22 average	140K	1.1%	Form 4
Feb 11	Michael Thomas Henderson Chief Executive Officer	Sold10b5-1 plan 3 parts	20,000	$63.35 average	$1.27M	1.7%	Form 4
Feb 4	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan 5 parts	5,500	$65.79 average	362K	2.5%	Form 4
Feb 2	Jane Henderson Chief Financial Officer	Sold10b5-1 plan 3 parts	2,000	$65.81 average	132K	1.1%	Form 4
Jan 22	Peter Evan Harwin Director	SoldNo plan	1,750,000	$76.30	$134M	81%	Form 4
Jan 14	Michael Thomas Henderson Chief Executive Officer	Sold10b5-1 plan 6 parts	20,000	$81.11 average	$1.62M	1.6%	Form 4
Jan 7	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan 4 parts	18,700	$77.84 average	$1.46M	8.1%	Form 4
Jan 2 – 6	Jane Henderson Chief Financial Officer	Sold10b5-1 plan 3 parts	8,000	$76.14 average	609K	4.1%	Form 4
Dec 19, 2025	Jane Henderson Chief Financial Officer	Sold10b5-1 plan	1,500	$80.00	120K	0.8%	Form 4
Dec 10, 2025	Michael Thomas Henderson Chief Executive Officer	Sold10b5-1 plan 3 parts	20,000	$75.38 average	$1.51M	1.6%	Form 4
Dec 4, 2025	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan	10,900	$75.00	818K	3.9%	Form 4
Dec 4, 2025	Jane Henderson Chief Financial Officer	Sold10b5-1 plan	1,500	$75.00	113K	0.8%	Form 4
Dec 4, 2025	Michael Thomas Henderson Chief Executive Officer	Sold10b5-1 plan	40,000	$75.01	$3M	3.1%	Form 4
Nov 25, 2025	Jane Henderson Chief Financial Officer	Sold10b5-1 plan	1,500	$70.00	105K	0.8%	Form 4
Nov 14, 2025	Jane Henderson Chief Financial Officer	Sold10b5-1 plan	2,000	$65.00	130K	1.0%	Form 4
Nov 13, 2025	Michael Thomas Henderson Chief Executive Officer	Sold10b5-1 plan 4 parts	20,000	$63.01 average	$1.26M	1.5%	Form 4
Nov 11, 2025	Jane Henderson Chief Financial Officer	Sold10b5-1 plan	1,000	$60.00	60K	0.5%	Form 4
Nov 5, 2025	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan 4 parts	10,785	$55.07 average	594K	3.7%	Form 4
Oct 1, 2025	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan	5,110	$39.80	203K	1.8%	Form 4
Sep 3, 2025	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan 2 parts	2,725	$37.87 average	103K	1.2%	Form 4
Aug 6, 2025	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan	2,725	$37.78	103K	1.1%	Form 4
Jul 2, 2025	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan 3 parts	10,090	$45.09 average	455K	4.1%	Form 4
Jun 4, 2025	Carl Dambkowski Chief Medical Officer	Sold10b5-1 plan	2,725	$36.96	101K	1.1%	Form 4

Aug 510b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 5,500 at $134.17
738K
3.2% of stake
Jul 810b5-1 plan
Michael Thomas Henderson
Chief Executive Officer · sold 20,000 at $133.63
$2.67M
2.1% of stake
Jul 110b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 5,500 at $132.74
730K
3.0% of stake
Jun 2210b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 26,400 at $132.60
$3.5M
13% of stake
Jun 2210b5-1 plan
Michael Thomas Henderson
Chief Executive Officer · sold 80,000 at $132.54
$10.6M
7.3% of stake
Jun 1010b5-1 plan
Michael Thomas Henderson
Chief Executive Officer · sold 20,000 at avg $83.38
$1.67M
1.8% of stake
Jun 310b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 5,500 at $78.71
433K
2.6% of stake
May 1310b5-1 plan
Michael Thomas Henderson
Chief Executive Officer · sold 20,000 at avg $82.09
$1.64M
1.8% of stake
May 610b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 5,500 at avg $84.14
463K
2.6% of stake
May 110b5-1 plan
Jane Henderson
Chief Financial Officer · sold 2,000 at avg $82.04
164K
1.1% of stake
Apr 1610b5-1 plan
Jane Henderson
Chief Financial Officer · sold 2,000 at $90.00
180K
1.1% of stake
Apr 810b5-1 plan
Michael Thomas Henderson
Chief Executive Officer · sold 20,000 at avg $82.58
$1.65M
1.7% of stake
Apr 110b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 5,500 at avg $84.84
467K
2.6% of stake
Apr 110b5-1 plan
Jane Henderson
Chief Financial Officer · sold 2,000 at avg $85.01
170K
1.1% of stake
Mar 2510b5-1 plan
Jane Henderson
Chief Financial Officer · sold 2,000 at $85.00
170K
1.1% of stake
Mar 1110b5-1 plan
Michael Thomas Henderson
Chief Executive Officer · sold 20,000 at avg $74.78
$1.5M
1.7% of stake
Mar 410b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 5,500 at avg $71.06
391K
2.6% of stake
Mar 210b5-1 plan
Jane Henderson
Chief Financial Officer · sold 2,000 at avg $70.22
140K
1.1% of stake
Feb 1110b5-1 plan
Michael Thomas Henderson
Chief Executive Officer · sold 20,000 at avg $63.35
$1.27M
1.7% of stake
Feb 410b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 5,500 at avg $65.79
362K
2.5% of stake
Feb 210b5-1 plan
Jane Henderson
Chief Financial Officer · sold 2,000 at avg $65.81
132K
1.1% of stake
Jan 22No plan
Peter Evan Harwin
Director · sold 1,750,000 at $76.30
$134M
81% of stake
Jan 1410b5-1 plan
Michael Thomas Henderson
Chief Executive Officer · sold 20,000 at avg $81.11
$1.62M
1.6% of stake
Jan 710b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 18,700 at avg $77.84
$1.46M
8.1% of stake
Jan 2 – 610b5-1 plan
Jane Henderson
Chief Financial Officer · sold 8,000 at avg $76.14
609K
4.1% of stake
Dec 19, 202510b5-1 plan
Jane Henderson
Chief Financial Officer · sold 1,500 at $80.00
120K
0.8% of stake
Dec 10, 202510b5-1 plan
Michael Thomas Henderson
Chief Executive Officer · sold 20,000 at avg $75.38
$1.51M
1.6% of stake
Dec 4, 202510b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 10,900 at $75.00
818K
3.9% of stake
Dec 4, 202510b5-1 plan
Jane Henderson
Chief Financial Officer · sold 1,500 at $75.00
113K
0.8% of stake
Dec 4, 202510b5-1 plan
Michael Thomas Henderson
Chief Executive Officer · sold 40,000 at $75.01
$3M
3.1% of stake
Nov 25, 202510b5-1 plan
Jane Henderson
Chief Financial Officer · sold 1,500 at $70.00
105K
0.8% of stake
Nov 14, 202510b5-1 plan
Jane Henderson
Chief Financial Officer · sold 2,000 at $65.00
130K
1.0% of stake
Nov 13, 202510b5-1 plan
Michael Thomas Henderson
Chief Executive Officer · sold 20,000 at avg $63.01
$1.26M
1.5% of stake
Nov 11, 202510b5-1 plan
Jane Henderson
Chief Financial Officer · sold 1,000 at $60.00
60K
0.5% of stake
Nov 5, 202510b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 10,785 at avg $55.07
594K
3.7% of stake
Oct 1, 202510b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 5,110 at $39.80
203K
1.8% of stake
Sep 3, 202510b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 2,725 at avg $37.87
103K
1.2% of stake
Aug 6, 202510b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 2,725 at $37.78
103K
1.1% of stake
Jul 2, 202510b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 10,090 at avg $45.09
455K
4.1% of stake
Jun 4, 202510b5-1 plan
Carl Dambkowski
Chief Medical Officer · sold 2,725 at $36.96
101K
1.1% of stake

How to read this. Insiders sell for many reasons: taxes, diversifying, a house. Open-market buys are rarer and say more. A 10b5-1 plan is a trading schedule set up months in advance, so those sales were not timed on news. Large holders (funds and 10% owners) are listed under Everything but not counted as insiders. If you own or watch APGE, we send a push when an executive buys or makes a large sale outside a plan.

Source: SEC Form 4 filings, filed within two business days of each trade and checked for new ones every hour.

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Held by ETFs

APGE is in 36 US ETFs. The largest of them, with APGE's weight in each:

Spot a number that looks wrong? Check it in APGE's SEC filings or

Download this analysis as a PDF (Pro)

Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.

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