Day One Biopharmaceuticals, Inc.

DAWN

Day One Biopharmaceuticals, Inc.

DAWN/Pharmaceutical Preparations/DE

Day One Biopharmaceuticals, Inc., or the Company or Day One, is a biopharmaceutical company dedicated to developing and commercializing targeted therapies for people of all ages with life-threatening diseases. At Day One, we aim to identify and develop breakthrough medicines with the goal of improving the outcomes and life trajectories of patients of any age facing serious diseases starting fro…

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ProfitabilityUnprofitable GrowthAccelerating Cash FlowCash burn ValuationN/A

What stands out

The business is unprofitable at the operating level (-80.76% margin). The thesis depends entirely on whether and when it reaches sustainable profitability.

What's changing

Revenue up 20.6% YoY with margins expanding 84.9pp.

What deserves caution

Negative free cash flow of -$104M. The business is consuming cash, not generating it.

Profitability & Returns

TTM as of 2025-12 · YoY vs prior year · ROIC = NOPAT / invested capital

Revenue (TTM)

$158M

▲ +20.6% YoY

Net Income (TTM)

-$107.32B

▼ -12.4% YoY

Op. Margin

-80.76%

▲ +84.9pp YoY

ROIC

-21.26%

▲ +19.0pp YoY

Cash Flow & Balance Sheet

FCF = operating cash flow + capex · Net debt = total debt − cash · Balance sheet from latest filing

FCF (TTM)

-$104M

▼ -29.6% YoY

Op. Cash Flow (TTM)

-$104M

▼ -32.8% YoY

Net Debt

-$438M

Net Cash Position

Cash & Equiv.

$441M

Continue Research

Quality Scorecard

Is this a high-quality business?

Dividends

Payout safety and growth

DCF Valuation

What is it worth?

Financials

Full income, cash flow, balance sheet

SourceComputed from the 10-Q filed 24 Feb 2026, covering the period ending 31 Dec 2025, as reported to the SEC. Data last refreshed 25 Sept 2026. How this is calculated.

Fiscal year ends Dec. Sector medians are approximate S&P 500 benchmarks and update periodically.

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Spot a number that looks wrong? Check it in DAWN's SEC filings or

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Data sourced from SEC EDGAR filings and third-party price providers. Scores, valuations, and metrics are algorithmic estimates. This is not investment advice. See our Terms and Methodology.

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